Backed by Research. Driven by Results.

Clinical Research

At Spinal Simplicity, we are committed to advancing the field of spine care through rigorous clinical research and evidence-based solutions. Below, you will find peer-reviewed publications and clinical studies demonstrating the safety, efficacy, and biomechanical stability related to our core technologies.

Minuteman® Studies

Minuteman® is a minimally invasive, interspinous-interlaminar fusion device designed to provide stabilization and fusion for patients suffering from segmental degenerative instabilities such as lumbar spinal stenosis and spondylolisthesis.

  1. Posterior Lateral Arthrodesis as a Treatment Option for Lumbar Spinal Stenosis

    • Summary: This study evaluates the effectiveness of the Minuteman® device in providing pain relief and functional improvement in patients with lumbar spinal stenosis.
    • Link: Read Full Study

  2. Instrumented Posterior Arthrodesis of the Lumbar Spine: A Prospective Study

    • Summary: Prospective evaluation of radiographic fusion outcomes in patients receiving instrumented posterior arthrodesis of the lumbar spine using a minimally invasive interspinous fixation device.
    • Link: Read Full Study

  3. 24-Month Outcomes of Indirect Decompression Using a Minimally Invasive Interspinous Fixation Device vs. Standard Open Direct Decompression

    • Summary: An early stage multicenter, prospective randomized control trial with 5-year follow-up to compare the efficacy of a MIS lateral interspinous fusion device (Minuteman) to open direct surgical decompression in lumbar spinal stenosis. Two-year results presented.
    • Link: Read Full Study

  4. Interspinous Interbody Fusion via a Strictly Lateral Surgical Approach

    • Summary: A biomechanical stabilization comparison of interspinous-interbody fusion via a strictly lateral surgical approach versus constructs requiring both lateral and posterior approaches.
    • Link: Read Full Study

  5. Single Position, Single Incision Approach for Lateral Interbody Fusion with Supplemental Posterior Fixation

    • Summary: Compares perioperative, clinical, and radiographic outcomes of lateral lumbar interbody fusion (LLIF) followed by posterior fixation in three patient cohorts treated via different minimally invasive stabilization workflows.
    • Link: Read White Paper

Intralink®* Research

IntraLink®* is a novel injectable technology offering biomechanical stability with a minimally disruptive approach, designed to optimize outcomes while reducing procedural complexity. 

  1. Pathomechanics of Early-Stage Lumbar Intervertebral Disc Degradation Leading to Discogenic Pain—A Narrative Review

    • Summary: A review of emerging intradiscal treatment strategies. Understanding the characteristics of progressive tissue degradation, especially the degradation that accumulates prior to the typical onset of pain and disability, is critically important.
    • Link: Read Full Study (Bioengineering Journal, 2024)

  2. A Self-Polymerizing Mesh of Nano-Tethers for the Mechanical Constraint of Degraded Intervertebral Discs—A Review of 25 Years of Pre-Clinical and Early Clinical Research

*IntraLink is not FDA cleared and is not available on the market.

Liberty-SI™ Research

The Liberty SI™ Fusion System is intended for sacroiliac (SI) joint fusion for conditions including SI joint disruptions and degenerative sacroiliitis. The procedure involves the lateral insertion of 1 or 2 titanium implants transfixing across the ilium and sacrum, designed to apply a compressive force to stabilize and fuse the SI Joint. Liberty SI™ is single use and provided sterile.

  1. Anatomic Evaluation of Sacroiliac Joint Dimensions: An Imaging Series Study to Define Safety Parameters

    • Summary: An evaluation of SI joints to determine safety zone measurements for the lateral approach to SI joint fusion.
    • Link: Read Full Abstract

Stay Informed 

Spinal Simplicity continues to invest in clinical research and innovation to drive the future of minimally invasive spine care. Please check back regularly for new publications and ongoing study updates.